[Ontology-editors] question about cellular component organization (from bp-xp-cc evaluation)
Midori Harris
midori at ebi.ac.uk
Tue Jun 16 09:11:10 PDT 2009
Hi,
So I finally overcame my fear of OBO-Edit making mincemeat of unrecognized
relations, and loaded the bp-xp-cc imports into OE for the first time in
months. The very first implied link in the list (upon Edit -> Assert
implied links) raises a question:
Assert: protein complex assembly is_a cellular macromolecular complex
assembly
I found the explanation a bit bewildering, but I think I see where the
implication is coming from. We've deliberately created separate terms for
protein complex assembly and cellular protein complex assembly (with
parallel structures for macromolecular complex assembly and m. c. subunit
organization) because some complexes are assembled at the
multicellular-organism level. The circulating lipoprotein complexes --
HDL, LDL, etc. -- are examples.
So it seems that, instead of asserting the implied link, we actually have
to move cellular component organization and cellular component biogenesis
directly under biological process, not under cellular process. This will
fix a bunch of other implied links too, I think.
I've also put this on the wiki:
http://wiki.geneontology.org/index.php/XP:biological_process_xp_cellular_component#2009-06-16
Comments welcome!
cheers,
m
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