substrates

J Clark jclark at ebi.ac.uk
Tue Apr 24 04:52:57 PDT 2007


Great! Thanks :-)

Jen

Peter D'Eustachio wrote:

> Hi Jen
> 
> Yes - that's how we use them. When we want to talk about the behavior of 
> albumin, we would use a "binding" term.
> 
> Peter
> 
> ----- Original Message ----- From: "J Clark" <jclark at ebi.ac.uk>
> To: "Peter D'Eustachio" <deustp01 at med.nyu.edu>
> Cc: <transport at genome.stanford.edu>
> Sent: Tuesday, April 24, 2007 6:40 AM
> Subject: Re: substrates
> 
> 
>> Hi Peter,
>>
>> Thanks, I see what you mean. If I move these terms under the term 
>> 'transmembrane transporter activity' would you be happy with that?
>>
>> Thanks,
>>
>> Jen
>>
>> Peter D'Eustachio wrote:
>>
>>> Narrow answer: No.
>>>
>>> Broad, somewhat tangential answer: yes, maybe. Biologists certainly 
>>> talk about serum albumin and cortisol binding globulin as 
>>> "transporters" of the hydrophobic small molecules that bind to them 
>>> in the blood and thus move from tissue to tissue, but this clearly 
>>> amounts to overloading of the word "transport" as far as we are 
>>> concerned.
>>>
>>> Peter D'Etc
>>>
>>> ----- Original Message ----- From: "J Clark" <jclark at ebi.ac.uk>
>>> To: <transport at genome.stanford.edu>
>>> Sent: Monday, April 23, 2007 10:44 AM
>>> Subject: substrates
>>>
>>>
>>>> Hi,
>>>>
>>>> Can anybody think of any example of transport of the following
>>>> substrates (belonging in the function ontology) that is not
>>>> straightforward transport from one side of a membrane to another?
>>>>
>>>> organic acid transporter activity
>>>> tricarboxylic acid transporter activity
>>>> carbohydrate transporter activity
>>>> alcohol transporter activity
>>>>
>>>> Thanks,
>>>>
>>>> Jen
>>>>
>>>>
>>>>
>>
>> -- 
>> Gene Ontology Consortium
>> EMBL-European Bioinformatics Institute 

-- 
Gene Ontology Consortium
EMBL-European Bioinformatics Institute



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